Basic Information
VIS ID
TVIS10002180
Fusion event
HBV-MIR5009 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
28737622/27365303 (Hg38)
End
28737622/27365303 (Hg38)
Location type
ncRNA_intronic
Target gene
MIR5009
Nearest miRNA
hsa-let-7c/Upstream/411260; hsa-mir-3197/Downstream/3009991;
Nearest TSS
ENST00000624081/Upstream/4139; ENST00000426418/Downstream/83276;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/221316, chr21-CpG: 29/Downstream/1519800
Upstream sequence
gacaggttttaccatgttggccaggatgttctcaatctcctgacctcatgacctgcccgcctctgcctctcaaagttcttggattacaggcgtgagccac
Downstream sequence
cacgcccagccaaatatatacaattttttatttgtcaattctaccttgatatagctgaaaaaGAGAAAAGGCAATTTATTTGCTCCATCAGCTGACAGTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate