Basic Information
VIS ID
TVIS10002183
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
51364404/53838034 (Hg38)
End
51364404/53838034 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/600844; hsa-mir-122/Downstream/1641187;
Nearest TSS
ENST00000575820/Upstream/256975; ENST00000577612/Downstream/322079;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1495682, chr18-CpG: 59/Downstream/386365
Nearby gene
DCC(-302131) ; MBD2(+313567) ;
Nearest cancer related gene
DCC(TSG, -302131) ;
Upstream sequence
ATTTTTTTAATCTCAGAATGCTCTCCTAATAGCCAGAACCCATTTTTCTTCCTTGTTGCTGGAAATTTCTACCTGAATATTCAGAAACAATAATTCAGTC
Downstream sequence
TCCTAAACTCTTCAAGTTCCCCTTAAAAGTGTATTTTTTCGTGCACCATGATCTTGATGCACAGAACCTCTATCCTTGTTCCCCATTTTGGAAGGCTAAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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