MOB2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002190
Fusion event
HBV-MOB2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
1677246/1656016 (Hg38)
End
1677246/1656016 (Hg38)
Location type
Intronic
Target gene
MOB2
Nearest miRNA
hsa-mir-210/Upstream/399346; hsa-let-7a-2/Downstream/203448;
Nearest TSS
ENST00000527297/Upstream/26241; ENST00000538190/Downstream/7327;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/3022, chr11-CpG: 21/Downstream/38101
Upstream sequence
TCCCTGGTGTAGAATGGTTCCTGGGAGTCTGGAAGAGGTGCCATTTCTCACGCGCCTGTCGGGGATGGACTGACAGCTGCAGGACCCACCTCGCCGCTTC
Downstream sequence
TAGCTGTGGGTCCATGCAGCCAACACAGAGGTTTGTGGTCACTGAGGACATTCGTGCAGACACTTTGTCCAGTGCCCGAGGGGACAGCTGCAGGCCAGCT
Target sequence
ttgaattttatcaaatgttttttcagtatcaaatgaaatgatcatatagtttttctcagtatctaatgaaatgatcatatagtttttgtccttcattctgttgatatgatgtatcacagtgattgatctgtgcatgttgaaccatccttacctccctgggataaatcccacttggtcatgataaatgatctttttgatgtgttgttagatttggcttgctagtgttttgttgaggatttctgcatcaatgttcat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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