Basic Information
VIS ID
TVIS10002207
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
178351553/177430399 (Hg38)
End
178351553/177430399 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/3006535; hsa-mir-1305/Downstream/4738894;
Nearest TSS
ENST00000502981/Upstream/73367; ENST00000507023/Downstream/9225;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/120293, chr4-CpG: 52/Downstream/11686
Nearby gene
NEIL3(-67461) ; AGA(+376) ;
Upstream sequence
ACTTTAATCTGCATAATAATataacacgtaaatacatatctccagccaaatttctctcctttgctccaaacccagccaaaactacctattggacttctcc
Downstream sequence
GCAAATATACAAAAGTATCATCTTAATGTAACCGCAAGTTTAAATCTGATTTTTTTCTTTTTCCAAGGCCCAGCACCAGGTTTAAGCAGGTTAGCATACC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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