Basic Information
VIS ID
TVIS10002215
Fusion event
HBV-LSM8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q31.31
Reference genome
GRCh37/hg19
Start
117823227/118183173 (Hg38)
End
117823227/118183173 (Hg38)
Location type
Promoter
Target gene
LSM8
miRNAs that regulate target gene
hsa-mir-4762-3p ; hsa-mir-1273e ; hsa-mir-3192-3p ; hsa-mir-6815-3p ; hsa-mir-5692a ; hsa-mir-548c-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-8083 ; hsa-mir-8063 ; hsa-mir-129-5p ; hsa-mir-138-2-3p
Nearest miRNA
hsa-mir-10525/Upstream/1162854; hsa-mir-10399/Downstream/8874915;
Nearest TSS
ENST00000635602/Upstream/179128; ENST00000411938/Downstream/859;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/309362, chr7-CpG: 58/Downstream/757
Upstream sequence
TTCCTGGAATCAAATCAGGATGTTACTCCTGCTTGGCTCTGCCTTGGTGCTGAGGCTGCTGTTTTTCAACTGCCATGTAGCTCCAAGTAATTGCCAGCTG
Downstream sequence
TTTCTAACTTCAAGCTCTCTCAAGTTAGGGCAACAGTAAATGAAGTGGGAACAGTATCGCATTGGGAAATATCTGAAATGATACCTATGGGACTATCtaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate