Basic Information
VIS ID
TVIS10002220
Fusion event
HBV-chr21 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
9753889/8865056 (Hg38)
End
9753889/8865056 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10396b/Upstream/428682; hsa-let-7c/Downstream/121943;
Nearest TSS
ENST00000624081/Upstream/105975; ENST00000624052/Downstream/153614;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/44658, chr21-CpG: 253/Downstream/121553
Nearby gene
MIR3648-1(+71943) ;
Upstream sequence
ATGACTGTAATTTGTTTTCATAGAAAATGTTGTAACTTCATAGGATAGTATCATATTAACATAATTGAAAAGAATAGTGTTGGGTGATTTATTGGGAAGA
Downstream sequence
AATTAATTAGAGAAGCTTTGCCTGATTAAAAGTTCATTAGAAACATTATGGCTTATAACGTAGTATTAAATTCAGGGACATAATAGGAAAGAAGTTGAGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate