Basic Information
VIS ID
TVIS10002221
Fusion event
HBV-MIR548I4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q35
Reference genome
GRCh37/hg19
Start
147176204/147479112 (Hg38)
End
147176204/147479112 (Hg38)
Location type
ncRNA_intronic
Target gene
MIR548I4
Nearest miRNA
hsa-mir-10399/Upstream/100991; hsa-mir-153-2/Downstream/3759309;
Nearest TSS
ENST00000635602/Upstream/381503; ENST00000637654/Downstream/159697;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1362120, chr7-CpG: 33/Downstream/860290
Upstream sequence
TTCTCAGTGCCTTTGCTCTTTTTGTTCCCATATTCTTTGGCCATCTCCATCCTAGACCTGGTGCATGCCTTCTAATCCTTAACGCTAGCAGCATTTTCTC
Downstream sequence
CATTCTGTGCTTAACTAAACATGCAGGCCCTTGTCTTCCCTCCACGTAGAAGGGGATTCCTCCTCCTTCCAGGCTACTCAAGTCTAAACTTTCTTTCAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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