DCLK1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002229
Fusion event
HBV-DCLK1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
36621174/36047037 (Hg38)
End
36621174/36047037 (Hg38)
Location type
Intronic
Target gene
DCLK1
miRNAs that regulate target gene
hsa-mir-137
Nearest miRNA
hsa-mir-2276/Upstream/11884533; hsa-mir-1267/Downstream/3616997;
Nearest TSS
ENST00000623511/Upstream/191176; ENST00000379848/Downstream/84269;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/568055, chr13-CpG: 75/Downstream/83866
Upstream sequence
TCTTTCTAAATAGTCTGGCATAAGaggaactcgagcaactcaattgcaagaaaacacataaaccaattaaaaaacgagcaaagcacttgaaaagacattt
Downstream sequence
ttcaaaaagtgacatacaaatggccaacaggtatacaaaaatatgctcaacatcagtagtcatcatgaaaatgcaaattaaaactacaatgagatatctc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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