VISDB Viral Integration Site DataBase

VIS ID

TVIS10002232

Fusion event

HBV-chr3 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr3

Cytoband

p21.31

Reference genome

Start

End

50228217/50190784 (Hg38)

Location type

Promoter;downstream

Target gene

GNAT1 ; SEMA3F

miRNAs that regulate target gene

hsa-mir-185-3p ; hsa-mir-4656 ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-6878-5p ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-4755-3p ; hsa-mir-6770-5p ; hsa-mir-6889-5p ; hsa-mir-3179 ; hsa-mir-6777-5p ; hsa-mir-3937 ; hsa-mir-6813-5p ; hsa-mir-6085 ; hsa-mir-3154 ; hsa-mir-6083 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-513b-5p ; hsa-mir-4662a-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-6853-3p ; hsa-mir-1206 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-4716-5p ; hsa-mir-103b ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-656-3p ; hsa-mir-493-5p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-let-7c-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-3145-3p

Nearest miRNA

hsa-mir-12127/Upstream/384539; hsa-let-7g/Downstream/36652;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/35087, chr3-CpG: 161/Downstream/2213

Nearest cancer related gene

GNAT1(TSG, No orient, 0)

Upstream sequence

aaaaaaagtgtggcacctccccactcgctctctcgctttcctgctccactgtggtaagacgtgccttgcttctccttcgccttctgccatgattgtaagg

Downstream sequence

ggcgggcacctgttgtcccagctactcaggaggctgaggcaggagaatggcgtgaacctgggaggtggagcttgcagtgagctgagattgcgccactgca