Basic Information
VIS ID
TVIS10002234
Fusion event
HBV-LOC105379107 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
103170397/103834696 (Hg38)
End
103170397/103834696 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
LOC105379107
Nearest miRNA
hsa-mir-10397/Upstream/3018131; hsa-mir-103a-1/Downstream/6679133;
Nearest TSS
ENST00000502646/Upstream/271903; ENST00000514769/Downstream/245215;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/574847, chr5-CpG: 253/Downstream/3834733
Nearby gene
NUDT12(-271907) ; RAB9BP1(+1264778) ;
Upstream sequence
GCCATCCACAGTCACCACACATCAGACCCCTGTGACCGATCGCCATCCACAGTCACCACACATCAGACCCCCGGGACCAACCGCCATCCACAGTCACCAC
Downstream sequence
tgggagaggggtgattcttcccccatgaggaagctgagtctcagagaggttaaacaacttgtccatggtcacacagctagtaagAAGTGCTAATAACAAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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