RGS13 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002241
Fusion event
HBV-RGS13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
192601042/192631912 (Hg38)
End
192601042/192631912 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA1K
Target gene
RGS13
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-146a-5p
Nearest miRNA
hsa-mir-101-1/Upstream/12193522; hsa-mir-1182/Downstream/84416;
Nearest TSS
ENST00000473358/Upstream/2827; ENST00000482095/Downstream/4226;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/5950963, chr1-CpG: 56/Downstream/176590
Upstream sequence
TCATATCTTTCAGAGGTTTTAAGATATAGTGTCATAATCCTAAAGAAAAACATTTGCCTTGTATTTTATTCTAGTTCCTTGTTTGACTAAGTCACAAGGA
Downstream sequence
CACCATTGTTTAAATTTGCATGCCTCATAAAAATATATATTTGTGTAAATTATACTTACAAAGCATCTCCAGATATATCTCATTAACCACTACACAAATT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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