Basic Information
VIS ID
TVIS10002280
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
18520257/20940296 (Hg38)
End
18520257/20940296 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-3156-2/Upstream/6110054; hsa-mir-1-2/Downstream/743222;
Nearest TSS
ENST00000575820/Upstream/5775829; ENST00000579454/Downstream/14574;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/5609121, chr18-CpG: 113/Downstream/170683
Nearby gene
ROCK1(+9446) ;
Nearest cancer related gene
ROCK1(OG, +9446) ;
Upstream sequence
tcaaacgaaatgttcaactccgttagttgaggacacacatcagaaacaagtttctgcgaatgcttctgtgtagtttttatgggaagatatttccttttcc
Downstream sequence
accataggcctgaaagcgctcgaaatgtccacttccagatactacagaaagagtgtttcaaacctgctctatgaaagggaatgttTTATATTTGTATGTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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