TCF7L1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002308
Fusion event
HBV-TCF7L1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
85367885/85140762 (Hg38)
End
85367885/85140762 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
TCF7L1
miRNAs that regulate target gene
hsa-mir-429 ; hsa-mir-200a-3p ; hsa-mir-200c-3p ; hsa-mir-141-3p ; hsa-mir-200b-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/5274179; hsa-mir-10b/Downstream/642838;
Nearest TSS
ENST00000437798/Upstream/6394; ENST00000442813/Downstream/72861;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/5292, chr2-CpG: 96/Downstream/186249
Upstream sequence
ggtggcaggtgcctgtaatcccgggtactcaggaggctgaggtaggagaatcacttgaacccaggaggcggcacctgtatcccagctacttgggaggctg
Downstream sequence
aggcaggagaattgctttaacctgggaggcagaggttgcagtgagctgagatcgcaccattgcactccaacctgggcaacaagagtgaaactccatctga
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate