Basic Information
VIS ID
TVIS10002315
Fusion event
HBV-RNA28SP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
133039237/132281664 (Hg38)
End
133039237/132281664 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
RNA28SP
Nearest miRNA
hsa-mir-1285-2/Upstream/24584; hsa-mir-10b/Downstream/152047;
Nearest TSS
ENST00000437798/Upstream/23695; ENST00000622084/Downstream/12713;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/23497, chr2-CpG: 79/Downstream/71079
Nearby gene
ANKRD30BL(-23695) ; GPR39(+134910) ;
Upstream sequence
gcactcgcattccacgcctggctccacgtcagccagccaggcttcttacccatttaaagttacagaatagactgagatcgtttcggccccaagacctctt
Downstream sequence
cccgctgaaatgtgggtgtagttggagagtagctgggacagacaggagggtccgtaagtggtgggggtgaagaggtgagagagactggtgagggtctcac
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate