Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002334
Fusion event
HBV-STK17A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
Start
End
43622603/43583004 (Hg38)
Location type
Promoter
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-4762-3p ; hsa-mir-3192-3p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-1305 ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-4670-3p ; hsa-mir-4635 ; hsa-mir-3668 ; hsa-mir-5680 ; hsa-mir-148a-5p ; hsa-mir-1250-3p ; hsa-mir-6828-3p ; hsa-mir-6873-3p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-767-3p ; hsa-mir-6728-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6824-5p ; hsa-mir-8060 ; hsa-mir-4639-3p ; hsa-mir-6783-5p
Nearest miRNA
hsa-mir-1183/Upstream/432010; hsa-mir-10399/Downstream/468762;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/137480, chr7-CpG: 88/Downstream/87
Upstream sequence
tttttttgcatgtctcatatatttttgttggaaactaaacactttagataatatagtgtagcaacacagtactgatcatccacttccaggggttattttt
Downstream sequence
gccggggccagaagcagggtgcagggcaggcgcggggcggtcacgggggcggggccggtcgcggggcgcggggcgggCCCGAGCTACCGGTAGTCTGCCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.