Basic Information
VIS ID
TVIS10002356
Fusion event
HBV-LOC107984419 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
30875696/30854149 (Hg38)
End
30875696/30854149 (Hg38)
Location type
Intronic
Target gene
LOC107984419
Nearest miRNA
hsa-mir-210/Upstream/2376601; hsa-let-7a-2/Downstream/4087688;
Nearest TSS
ENST00000527297/Upstream/267277; ENST00000528872/Downstream/52556;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/267568, chr11-CpG: 37/Downstream/515391
Nearby gene
MPPED2(-267766) ; DCDC1(+9454) ;
Upstream sequence
GCctcaactctgagtacaacaaggaaaagtggaaatttatagtcaagaagcagagttgtggggggtagagaggctcagtgtgaaaactggtaagaggaaa
Downstream sequence
cattagggataagagggcgatagcagctaaagcaacctaatggggttcttgctgaaggcaggccagggtgacatcacctgagggatggtggagcatgaag
Target sequence
AGCTAAACTTTCTCCTTCTCAGTCTCCtgctagttattctacatttgatcctctccatctctacatgatttctctgccttttgctgccctgctgtaagttccagaagtctagcctcttcaagctacatcactcagacactcgggccctctggttttcagtgggatttagacaatggcagtaactggaagaaatcagagtatgggaggcaaaagagatcaggctatttatttctccatccctatacttttcctgct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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