Basic Information
VIS ID
TVIS10002372
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
9398523/9398290 (Hg38)
End
9398523/9398290 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/3228855; hsa-mir-10398/Downstream/1041427;
Nearest TSS
ENST00000381078/Upstream/236513; ENST00000645232/Downstream/1006212;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/962382, chr6-CpG: 41/Downstream/570
Nearby gene
PRPF31(-612845) ; TFAP2A(+998393) ;
Nearest cancer related gene
TFAP2A(TSG, +998393) ;
Upstream sequence
ccgtctaggaagtgaggagcgtctctgcccggccgcccatcgtctgagatgtggggagcgcctctgccccgccgccccgtctgggagatgaggagcgtct
Downstream sequence
GCCTGATGTATTCATCACCAGACTGCAGACACCTAGTTAATCCATTTAGAACCTATCACCTCTGTTCATCGGCTCATAAACCTATTACATTGGAGGCGCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate