Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002376
Fusion event
HBV-ACTR3B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q36.2
Reference genome
End
152595063/152897978 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-379-3p ; hsa-mir-487a-3p ; hsa-mir-539-3p ; hsa-mir-127-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-4710 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-621 ; hsa-mir-4660 ; hsa-mir-6804-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-5690 ; hsa-mir-6760-5p ; hsa-mir-4779 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10399/Upstream/1464339; hsa-mir-153-2/Downstream/4676358;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/3357, chr7-CpG: 37/Downstream/5433
Upstream sequence
TATCAACAAGTTTAGGCCAGGTCCAACAAGGAAAAAAGAAAAGGCAAAACTCCCAGCAACCTCTTTTTTGGGTCTTCCTTCCTGTGCCCTCATCGCCGGT
Downstream sequence
aaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaacccccacccctcgccacccccacttcctgaagtcagtgactagttgaagt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.