PAPPA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002401
Fusion event
HBV-PAPPA2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
176427843/176458707 (Hg38)
End
176427843/176458707 (Hg38)
Location type
Promoter
Target gene
PAPPA2
Nearest miRNA
hsa-mir-101-1/Upstream/490228; hsa-mir-1182/Downstream/570656;
Nearest TSS
ENST00000473358/Upstream/251059; ENST00000493665/Downstream/4464;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/251032, chr1-CpG: 44/Downstream/705549
Upstream sequence
ACAGGAATACTGTGGCAAAAAAACCAATAATACAATGACGGAAATCCTTAGCTTTGTGTCCAGGGAAAGCTTGGTTTAGCTGTGAGTGAGTGAAACCAGC
Downstream sequence
TCAATAAACGTCAGCAATTTGAAGACATCTGGTCTTTATTTTTGGACTTTGGTACACTGAAGAGGATTATGGTTATACGATGTAGAGGCCATTTAGTTTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate