Basic Information
VIS ID
TVIS10002419
Fusion event
HBV-chr3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
24581553/24540062 (Hg38)
End
24581553/24540062 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA3A
Nearest miRNA
hsa-mir-12127/Upstream/4402421; hsa-let-7g/Downstream/1124811;
Nearest TSS
ENST00000440867/Upstream/40482; ENST00000455576/Downstream/147857;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/17977, chr3-CpG: 106/Downstream/289121
Nearby gene
RARB(+888201) ;
Nearest cancer related gene
RARB(TSG, +888201) ;
Upstream sequence
ctatagaactttaatcgaaattgaattaaatcctttcgagtactaccaccaccttatcaacaaagtttatgtattaggttagtgcaaaagtagttgtggg
Downstream sequence
ttGGTCAGAAGGGTACACTTGTTTCTGGATTGCTGGTGTTCAACGGGCATCTTGTATATAACGCATGGCTATATATGGAGGCATTGCCCTGACTCCCAGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate