Basic Information
VIS ID
TVIS10002422
Fusion event
HBV-chr12 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
33695936/33543001 (Hg38)
End
33695936/33543001 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/7668922; hsa-let-7i/Downstream/8780699;
Nearest TSS
ENST00000382841/Upstream/103182; ENST00000541178/Downstream/479280;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/102886, chr12-CpG: 25/Downstream/479294
Nearby gene
SYT10(-103182) ; ALG10(+479280) ;
Upstream sequence
gttagtagaaatgtaaaatggtgtagccactatgaaaagcagtatagaggtctctcaaaaaattaaaactagaactaAGgtcatatatcacataacattt
Downstream sequence
tggttaacaacagaacacatatactacatttgtcccataagattataatacatttttttactgtatcttttctgtttttagatatttttagacagacaag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate