Basic Information
VIS ID
TVIS10002427
Fusion event
HBV-FAM27E4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q13
Reference genome
GRCh37/hg19
Start
45023267/61887115 (Hg38)
End
45023267/61887115 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9F
Target gene
FAM27E4
Nearest miRNA
hsa-mir-101-2/Upstream/20653280; hsa-let-7a-1/Downstream/8922860;
Nearest TSS
ENST00000422679/Upstream/18388; ENST00000417850/Downstream/23878;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/12010, chr9-CpG: 80/Downstream/4005
Nearby gene
FAM27C(-31775) ;
Upstream sequence
ttgttaactatattcaccttgctgtacctcacatctccaaagcctcttcatctcatataactaaatttgcactttggccaacatctccctattgtctcct
Downstream sequence
acggagtctcgctctgtcgcccaggccggactgcggactgcagtggcgcaatctcggctcactgcaagctccgcttcccgggttcacgccattctcctgc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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