EYA4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002446
Fusion event
HBV-EYA4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
133760193/133439055 (Hg38)
End
133760193/133439055 (Hg38)
Location type
Intronic
Target gene
EYA4
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-203a-3p ; hsa-mir-27b-3p ; hsa-mir-224-5p ; hsa-mir-148b-3p ; hsa-mir-132-3p ; hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-10398/Upstream/1323792; hsa-mir-1202/Downstream/1540283;
Nearest TSS
ENST00000381078/Upstream/78850; ENST00000497350/Downstream/409;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/196288, chr6-CpG: 43/Downstream/224928
Nearest cancer related gene
EYA4(TSG, No orient, 0)
Upstream sequence
ttagtcttagattatgtccttctttttgttgttgaaatattcttctgggaaatgatgttgtagtaagtggtagagaggccctttgttttagtttgctttt
Downstream sequence
aaaaaaaaaaaaaaaaaaaaaGTCTTTGGGTTGGGCGAGTCTAGTAGAAGATAATGACTTTACGAGCATTTAGCATTGACTGTAATTAAGTCTGTTATCG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate