Basic Information
VIS ID
TVIS10002455
Fusion event
HBV-LINC00578 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q26.32
Reference genome
GRCh37/hg19
Start
177455247/177737459 (Hg38)
End
177455247/177737459 (Hg38)
Location type
ncRNA_intronic
Target gene
LINC00578
Nearest miRNA
hsa-let-7g/Upstream/1222308; hsa-mir-1224/Downstream/6149341;
Nearest TSS
ENST00000440867/Upstream/53832; ENST00000434309/Downstream/79406;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/539393, chr3-CpG: 63/Downstream/1334058
Upstream sequence
TCATCTTGTTTGTTTCCTTAGGGAAGGAATGCATACAGATCATTTTCCCATAATTTGGAAAGTATATTACTTATTTATTTTCTCTTGAAGGGCTTTATCT
Downstream sequence
TTTTTCATCTTTAAAAAACATACAGACAAGCGTTTGTTTTGTTCTATTAAAAAACTGAGTGCCCAGTGGACAAAGGACATCCTAGTCCATTATGAAATTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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