Basic Information
VIS ID
TVIS10002467
Fusion event
HBV-HERC2P9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
28900991/28655845 (Hg38)
End
28900991/28655845 (Hg38)
Location type
ncRNA_exonic
Target gene
HERC2P9
Nearest miRNA
hsa-mir-1268a/Upstream/165000; hsa-mir-10393/Downstream/2409187;
Nearest TSS
ENST00000557528/Upstream/122831; ENST00000559709/Downstream/56478;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/66159, chr15-CpG: 118/Downstream/81678
Upstream sequence
GGCAGCTCCGTGAGTGTCCCCGGTCGAGCTCGCTGTTTGGTCTGCACTAGGCCCAGTTAGAGGACTACTTCCCCGACTCCGAGAACCCTGAAGTGGGGGG
Downstream sequence
CCTCATGGCGGTCCTGGCTGTGGTTGGAGGCATCGATGGTCGCCTGCGCCTGGGTGGCCAAGTTGTGCACGATGACTTTGGAGAAGTCACCATGACTCGC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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