Basic Information
VIS ID
TVIS10002471
Fusion event
HBV-HERC2P5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
32786508/32775187 (Hg38)
End
32786508/32775187 (Hg38)
Location type
Intronic
Target gene
HERC2P5
Nearest miRNA
hsa-mir-1225/Upstream/1881202; hsa-mir-11401/Downstream/1388391;
Nearest TSS
ENST00000527434/Upstream/34093; ENST00000569859/Downstream/34369;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/33658, chr16-CpG: 134/Downstream/35946
Nearby gene
TP53TG3B(-99060) ; SLC6A10P(+102289) ;
Upstream sequence
GGCAGCTCCGTGAGTGTCCCTGGTCGAGCTCACTGTTTGGTCTGCACTAGGCCCAGTTAGAGGACTACTTCCCCGACTCCGAGAACCCTGAAGTGGGGGG
Downstream sequence
CCTCATGGCGGTCCTGGCTGTGATTGGAGGCATCGATGGTCGCCTGTGCCTGGGCGGCCAAATTGTGCACGATGAGTTTGGAGAAGACACCGTGACTGGC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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