Basic Information
VIS ID
TVIS10002472
Fusion event
HBV-HERC2P8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
33106535/33095214 (Hg38)
End
33106535/33095214 (Hg38)
Location type
Intronic
Target gene
HERC2P8
Nearest miRNA
hsa-mir-1225/Upstream/2201229; hsa-mir-11401/Downstream/1068364;
Nearest TSS
ENST00000527434/Upstream/3625; ENST00000562827/Downstream/217;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/35221, chr16-CpG: 57/Downstream/33664
Nearby gene
SLC6A10P(-210072) ; TP53TG3C(+99050) ;
Upstream sequence
CAGTCACGGTGTCTTCTCCAAACTCATCGTGCACAATTTGGCCGCCCAGGCACAGGCGACCATCGATGCCTCCAATCACAGCCAGGACCGCCATGAGGCC
Downstream sequence
CCCCACTTCAGGGTTCTCGGAGTCGGGGAAGTAGTCCTCTAACTGGGCCTAGTGCAGACCAAACAGTGAGCTCGACCAGGGACACTCACGGAGCTGCCCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate