Basic Information
VIS ID
TVIS10002487
Fusion event
HBV-chr3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
GRCh37/hg19
Start
191475127/191757338 (Hg38)
End
191475127/191757338 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/1927329; hsa-mir-3137/Downstream/3377168;
Nearest TSS
ENST00000440867/Upstream/188803; ENST00000452657/Downstream/272542;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/427417, chr3-CpG: 24/Downstream/105801
Nearby gene
PYDC2(-295882) ; FGF12(+382055) ;
Upstream sequence
ggttgggtttagtgttagggtttagggttagggttagggttagggttgggttagggttagggttcgggttagggttagggttagggttagggttagggtt
Downstream sequence
CAGCTATGGTGAGAAATAAAAAAGTTTTGATGAAATAAATCCCACAATCAAAACTATGTTTTATAGAGAGAAGTAACTGTGTAACTAGTCTTTACGGAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate