APBA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002491
Fusion event
HBV-APBA2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
29214025/28921822 (Hg38)
End
29214025/28921822 (Hg38)
Location type
Intronic
Target gene
APBA2
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-615-3p
Nearest miRNA
hsa-mir-1268a/Upstream/430977; hsa-mir-10393/Downstream/2143210;
Nearest TSS
ENST00000557528/Upstream/185; ENST00000558206/Downstream/39482;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/34760, chr15-CpG: 62/Downstream/181616
Upstream sequence
GCCTCTTCTTGTGTCTGGAGATTCTGAGTGAGTAGAACCCGTTATGATCCCCACTGCACTTAATGTGGCATTCATGAATGAGTCTGGGCTGATGTGCTAA
Downstream sequence
TTGGGGGCCGTAAGAAGAGTTATAGCCACGATGGCCCTCACCTTTCTCTAATAAAAGCTTAAACACAGCTACGGTAAATATTTTTGCTTTCTGCTTTCAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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