UNC5A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002506
Fusion event
HBV-UNC5A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
176228562/176801561 (Hg38)
End
176228562/176801561 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA5G
Target gene
UNC5A
miRNAs that regulate target gene
hsa-mir-320a
Nearest miRNA
hsa-mir-10397/Upstream/172061; hsa-mir-1229/Downstream/2996717;
Nearest TSS
ENST00000502646/Upstream/58356; ENST00000513890/Downstream/8916;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/57766, chr5-CpG: 130/Downstream/8199
Nearest cancer related gene
UNC5A(TSG, No orient, 0)
Upstream sequence
AATTTTCTCTTGCTTCCATATATTTTGAGGAGGCCAAGTTATAGTCAGAAGGGCTTAACGTGGTCAGATGGTTTTGCAGATGGGCTTATAATACTTGAag
Downstream sequence
GTGTGCACATCCAGATGTGGGCtgtgtatatgtgtgtgtgtgtgttgtctgtgtttgtgtgtgtgcacatccaggtgtgggctgtgtgtatgtgtgtgtg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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