Basic Information
VIS ID
TVIS10002514
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
53247336/52381170 (Hg38)
End
53247336/52381170 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/4728427; hsa-mir-1243/Downstream/331512;
Nearest TSS
ENST00000502981/Upstream/302826; ENST00000503051/Downstream/247196;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/304088, chr4-CpG: 141/Downstream/277627
Nearby gene
SPATA18(-283878) ; USP46(+209791) ;
Upstream sequence
tccattccattccattccattccattccattccattccattcgactcgggttgattccaatccattccattccaatccattccattccattccattccat
Downstream sequence
caaacaattgaaaaggagagactcctccctaacaaattctatgaagccagtatcatcctgataccaaagcctggaagtgacacaactaaaaaagaaaact
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate