Basic Information
VIS ID
TVIS10002519
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
65262332/65035198 (Hg38)
End
65262332/65035198 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LINC02576 ; LOC107984063
Nearest miRNA
hsa-mir-1301/Upstream/509633; hsa-mir-10b/Downstream/1323051;
Nearest TSS
ENST00000437798/Upstream/4451; ENST00000475851/Downstream/21168;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/45120, chr2-CpG: 132/Downstream/20698
Nearby gene
SLC1A4(-11332) ; CEP68(+21163) ;
Upstream sequence
acccctcacctcagcctcccaaagtgctaggattacaggcgtgagccactgtgcctggccTTGACAATACTTTTATATCCTGGTATACTACAGTGAAGGT
Downstream sequence
AGGGGTTGTACTTAAGGTAATCAAGGGCTATTGTCTTTTAAATTGATATATAATAGTTGTACATGTATGGGGGGTAAGTAGCCTTCATTATAGAAGTAGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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