Basic Information
VIS ID
TVIS10002525
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p36.32
Reference genome
GRCh37/hg19
Start
4363250/4303190 (Hg38)
End
4363250/4303190 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/742400; hsa-mir-101-1/Downstream/1559482;
Nearest TSS
ENST00000473358/Upstream/283682; ENST00000633821/Downstream/108837;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/141578, chr1-CpG: 317/Downstream/350739
Nearby gene
RP13-614K11.1(-350607) ; SREBF2-AS1(+108861) ;
Upstream sequence
tccattccatttgattccattccgttccattccattgcattccattccattccattccattcgagtacattccattccattccattccattctactccac
Downstream sequence
tccacccgaccccaccccaccccaccccaccccaccccaccccaccccaccccaccccactccattccattccattccattccattccattccattccat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate