Basic Information
VIS ID
TVIS10002540
Fusion event
HBV-chr20 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
29818404/31230601 (Hg38)
End
29818404/31230601 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/5022323; hsa-mir-1-1/Downstream/376585;
Nearest TSS
ENST00000382410/Upstream/868871; ENST00000400552/Downstream/27063;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/308053, chr20-CpG: 20/Downstream/244645
Nearby gene
MLLT10P1(-180266) ; DEFB115(+27063) ;
Upstream sequence
atggaaaggaatggactgtaatggaaggaatggaatggaatgCACACGAATGTAACTGgaatggaatggaatcaaatggaatggacaggaatggaattaa
Downstream sequence
atggaatggaatggaatggattggaatggaatgaaatggaatggaatggaatggaatagaaaggaatggaatggaatgggattgaatggaatggaatgga
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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