Basic Information
VIS ID
TVIS10002604
Fusion event
HBV-IGK integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
89879140/89840330 (Hg38)
End
89879140/89840330 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
IGK
Nearest miRNA
hsa-mir-1285-2/Upstream/1027876; hsa-mir-10b/Downstream/6957948;
Nearest TSS
ENST00000437798/Upstream/509901; ENST00000429992/Downstream/11461;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/72229, chr2-CpG: 65/Downstream/397718
Nearby gene
MIR4436A(-767172) ; LSP1P4(+1945569) ;
Upstream sequence
caatggaatggaatcaataggaagggaatggaaagaaatgaaacggaacgaaatggaatggaacgaaatggaatggaatggaatggaatggaatggaacg
Downstream sequence
gaacggaatggaatggaatggaatggaatgcaatcaacccgagtggaatggaatggaatagaatgaattggaatggaatcaacacgaatggaatgcaatg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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