PCSK6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002606
Fusion event
HBV-PCSK6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
101924247/101384042 (Hg38)
End
101924247/101384042 (Hg38)
Location type
UTR3
Target gene
PCSK6
miRNAs that regulate target gene
hsa-mir-454-3p ; hsa-mir-6842-3p ; hsa-mir-647 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-1273e ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4529-5p ; hsa-mir-219b-3p ; hsa-mir-3190-5p ; hsa-mir-6782-3p ; hsa-mir-302f
Nearest miRNA
hsa-mir-10393/Upstream/2599540; hsa-mir-1302-10/Downstream/576417;
Nearest TSS
ENST00000557528/Upstream/1836; ENST00000328882/Downstream/59621;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/88301, chr15-CpG: 23/Downstream/14398
Upstream sequence
caggctagactcaaattcctgggctcaagcaatcctcctgcctcaacttccctagtagctgcgactataggcacacgtcattgctcctggcttaaagaga
Downstream sequence
actatgagtaaatattggtataggtggtgtctcggtgtggccaaagttatagagTATAGGAGACCCCAGACTCTTGTGACCTGAGGGTTCTTCCGTAATG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate