Basic Information
VIS ID
TVIS10002608
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
126921604/127585912 (Hg38)
End
126921604/127585912 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/8431196; hsa-mir-103a-1/Downstream/1511776;
Nearest TSS
ENST00000502646/Upstream/38077; ENST00000514851/Downstream/4798;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/67679, chr5-CpG: 200/Downstream/496990
Nearby gene
PRRC1(-30824) ; CTXN3(+63109) ;
Upstream sequence
CCCATCCCCCATTCTCGCaaaaaaaaaaaaaaaaaaaaaaaaGCCAAATTATTACCCCAAAGTGCTTTGAGCACTTTACAGTTTTTTTCCCCTCTGCCTC
Downstream sequence
agtagttacaatgtgaaccttacatcatgcaaagcctaaaatatttactttctggcccttgacagaaaaagtttgctgaactctgTAGTAGATTAATAGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate