ERBB4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002610
Fusion event
HBV-ERBB4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q34
Reference genome
GRCh37/hg19
Start
213002526/212137801 (Hg38)
End
213002526/212137801 (Hg38)
Location type
Intronic
Target gene
ERBB4
miRNAs that regulate target gene
hsa-mir-372-3p ; hsa-mir-19a-3p ; hsa-mir-302d-3p ; hsa-mir-146a-5p ; hsa-mir-145-5p ; hsa-mir-221-3p ; hsa-mir-302b-3p ; hsa-mir-193a-3p ; hsa-mir-146b-5p
Nearest miRNA
hsa-mir-10b/Upstream/4382920; hsa-mir-1244-1/Downstream/288462;
Nearest TSS
ENST00000437798/Upstream/12620; ENST00000434559/Downstream/291446;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1660989, chr2-CpG: 86/Downstream/399655
Nearest cancer related gene
ERBB4(TSG, No orient, 0)
Upstream sequence
gctggattaaatggtatttctgttttaggtctttaaggaatcaacacactgtcttccaaaatggttaaacaaatttatactcccaccaacagtgtataag
Downstream sequence
cactcctCCTGCTGAGCACCAAAAGAAACTATCAACAGAGTAAACAACACACTTTCAAGTACTAACTGTAATTGGGTGTTTGATAAGGAGACAGCCACCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate