Basic Information
VIS ID
TVIS10002620
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
5910453/5910340 (Hg38)
End
5910453/5910340 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/4201472; hsa-mir-10397/Downstream/917513;
Nearest TSS
ENST00000502646/Upstream/487598; ENST00000568962/Downstream/111943;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/22925, chr5-CpG: 53/Downstream/467838
Nearby gene
ICE1(-420106) ; LINC02145(+400101) ;
Upstream sequence
GGCCAGCGGCAGCACCTCGCGGTAGTGGCTGCGCAGCAGGGAGCGCACGGCTCGGCAGCGGGGAGCGCGCGGCATCGCGGGGGTGGCCGGGGCCAGGGCT
Downstream sequence
TCCCAGGTTGTCATAGAAACATGTATGCATTTCAGGCCATGAGGCCTTCGTTTGGGTTCAGAAAACATGAATTTTGCATGAATATGGCCAACATGCTTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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