Basic Information
VIS ID
TVIS10002623
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
172609128/173182125 (Hg38)
End
172609128/173182125 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA5G
Nearest miRNA
hsa-mir-10397/Upstream/266967; hsa-mir-12118/Downstream/121605;
Nearest TSS
ENST00000502646/Upstream/22149; ENST00000523205/Downstream/53081;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/124715, chr5-CpG: 38/Downstream/46712
Nearby gene
BNIP1(-17738) ; NKX2-5(+49979) ;
Upstream sequence
CAGATCCCCACCTACCCCACACATAAAAACCAATCCCACAGGTCCCCACCTACCCCACACATAGAAACCAATCCCACAGATCCCCACCTACCCCACGGAT
Downstream sequence
agaaaccatcactccccaactcagtccacatggggacagagctgacacaacccctgatgccagggttgaagaggtgacctggatggtcagggtcagagtg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate