hsa-mir-130b-3p _LIHC.png
PPARGC1A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002644
Fusion event
HBV-PPARGC1A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
24305761/24304138 (Hg38)
End
24305761/24304138 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
PPARGC1A
miRNAs that regulate target gene
hsa-mir-23a-3p ; hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-421 ; hsa-mir-425-3p ; hsa-mir-378a-5p ; hsa-let-7b-5p ; hsa-mir-130b-3p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-4775 ; hsa-mir-3124-3p ; hsa-mir-5011-5p ; hsa-mir-32-3p ; hsa-mir-5585-3p ; hsa-mir-3941 ; hsa-mir-8064 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-485-3p ; hsa-mir-485-5p ; hsa-mir-130a-3p ; hsa-mir-4311 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4668-5p
Nearest miRNA
hsa-mir-12113/Upstream/1788753; hsa-mir-1243/Downstream/216054;
Nearest TSS
ENST00000502981/Upstream/400049; ENST00000569621/Downstream/225941;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1787713, chr4-CpG: 266/Downstream/165939
Nearby gene
PPARGC1A(-414061) ; MIR573(+216054) ;
Upstream sequence
ccgcgatccggccactgcactacagcctgggtgacagagcaagactccgtctcaaaaaagaaaagaaaaaTctgggtgcggtgcctcccacctataatcc
Downstream sequence
ATTGTTCACTCAGCACAAGGATATTTTGATCTAATAAATGCTTATAGATGACCTGCTTGTGTGGCAATGGGGCAGCATTTCCAAGGGAAGCTTTGTGCAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate