VISDB Viral Integration Site DataBase

VIS ID

TVIS10002645

Fusion event

HBV-chr19 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr19

Cytoband

q13.2

Reference genome

Start

End

39135109/38644469 (Hg38)

Location type

Promoter;downstream

Fragile sites / regions

Target gene

ACTN4 ; EIF3K

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-935 ; hsa-mir-744-5p ; hsa-mir-744-5p ; hsa-mir-296-3p ; hsa-mir-769-5p ; hsa-mir-652-3p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-339-5p ; hsa-mir-324-3p ; hsa-mir-324-5p ; hsa-mir-378a-5p ; hsa-mir-320a ; hsa-mir-185-5p ; hsa-mir-23b-3p ; hsa-mir-182-5p ; hsa-mir-96-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-23a-3p ; hsa-mir-16-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-mir-142-5p ; hsa-mir-146a-3p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-3121-3p ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-4766-5p ; hsa-mir-548ap-5p ; hsa-mir-5571-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-5590-3p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-374a-5p ; hsa-mir-3191-5p ; hsa-mir-3921 ; hsa-mir-4653-5p ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-605-5p ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-2115-5p ; hsa-mir-7114-3p ; hsa-mir-1180-5p ; hsa-mir-4750-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-645 ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-193a-3p ; hsa-mir-1538 ; hsa-mir-3123 ; hsa-mir-3919 ; hsa-mir-4528 ; hsa-mir-4745-3p ; hsa-mir-654-3p ; hsa-mir-6740-3p ; hsa-mir-7112-5p

Nearest miRNA

hsa-mir-10395/Upstream/3298842; hsa-let-7e/Downstream/765154;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/25247, chr19-CpG: 57/Downstream/2953

Nearest cancer related gene

ACTN4(OG, No orient, 0)

Upstream sequence

CAAGAACAATATCAacaaaacttggctgagctggatgtggtggtacgtgttcacagtcgcagctactcagaaggctgaggtaggagaatcaagagtctga

Downstream sequence

gctcaacttgggcaaaatattgagaaccctgtctccaaaaacaaaaaaCTAAAACACTGGGCTggccgggtagagtggctcatgcccgtaatccctgcac