Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002659
Fusion event
HBV-SFPQ integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
Start
End
35668568/35202967 (Hg38)
Location type
Promoter
Target gene
miRNAs that regulate target gene
hsa-mir-141-3p ; hsa-mir-29b-3p ; hsa-mir-1229-3p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-331-3p ; hsa-mir-10a-5p ; hsa-mir-218-5p ; hsa-mir-498 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-1296-5p ; hsa-mir-6508-3p ; hsa-mir-5697 ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p ; hsa-mir-5694 ; hsa-mir-383-5p
Nearest miRNA
hsa-mir-12136/Upstream/533273; hsa-mir-101-1/Downstream/1958596;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9757, chr1-CpG: 69/Downstream/65655
Nearest cancer related gene
SFPQ(OG, No orient, 0)
Upstream sequence
AAGGAAAGAAATATTCAACAAATGGTATTAGAGTATTTAATTTGCtatatatgtatatatatgtatatatatgtatatatgtatatatatgtatatatgt
Downstream sequence
atatatatgtatatatgtatatatgtatatatgtatatatatgtgtatatatatgtatatatgtatatatatataATCAAACTGATTCTAGATGGATAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.