Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002673
Fusion event
HBV-NLRC5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
Start
End
57053402/57019490 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-216b-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-452-3p ; hsa-mir-6504-5p ; hsa-mir-4736 ; hsa-mir-3064-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-3126-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-149-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-1225/Upstream/115137; hsa-mir-11401/Downstream/752799;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/29634, chr16-CpG: 133/Downstream/72642
Upstream sequence
tgtctcaaaaaaaaaaGAGTTCCAGTTCAGAAGGGAAGAATTTGCTTAGCAAAAGAGGTGATGGTCtgtgttagctaggattagagttcactgtgagtag
Downstream sequence
cagaaagcactaaacaacagtggcttaaccagaatggaagtgtatttccctgccatgtaacagaagtccaaagtcagtgagcacagggcagatgggcagc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.