Basic Information
VIS ID
TVIS10002675
Fusion event
HBV-PMS2P5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
72510936/73096634 (Hg38)
End
72510936/73096634 (Hg38)
Location type
ncRNA_intronic
Fragile sites / regions
FRA7J
Target gene
PMS2P5
Nearest miRNA
hsa-mir-1183/Upstream/398656; hsa-mir-10399/Downstream/614683;
Nearest TSS
ENST00000635602/Upstream/127168; ENST00000437013/Downstream/208069;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/90239, chr7-CpG: 107/Downstream/58034
Upstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNctaaccctaaccctaaccctaaccctaaccctaacc
Downstream sequence
atatatatatacatatatatgtatatatatatatatatttttttttttagacagagtcgcactctgtcacccaggctggagtgcagtggcacagtctcag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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