Basic Information
VIS ID
TVIS10002686
Fusion event
HBV-LINC01435 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
109828998/108069240 (Hg38)
End
109828998/108069240 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LINC01435
Nearest miRNA
hsa-mir-107/Upstream/3800835; hsa-mir-202/Downstream/2828850;
Nearest TSS
ENST00000439456/Upstream/19894; ENST00000421481/Downstream/53;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/154034, chr10-CpG: 63/Downstream/396929
Nearby gene
SORCS1(-904532) ; RNU6-53P(+1101417) ;
Upstream sequence
AATATAGTTTTCTTAAATCACCCTATATAGATTTCTCCTACCTTTCATGAAAAGTACTTTAACTTCTCTCTGGGGCTCAATAGCTTCCCTGCCCTCAGGC
Downstream sequence
TGTGTTCTTTCAATGTGGCCGATCCCACTCCAGTTCCAGACATGGGCATAAGACTTAAGCCCAAGCCAAGAAACACATTTCATTCCCTTGACTATAAACA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate