FST _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002727
Fusion event
HBV-FST integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
52777374/53481544 (Hg38)
End
52777374/53481544 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5H
Target gene
FST
miRNAs that regulate target gene
hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-507 ; hsa-mir-557
Nearest miRNA
hsa-mir-10397/Upstream/14923983; hsa-mir-103a-1/Downstream/469960;
Nearest TSS
ENST00000502646/Upstream/918; ENST00000491717/Downstream/1150;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/862, chr5-CpG: 26/Downstream/414
Upstream sequence
GACCCAGGGCTGCCTCCAGGTCCGGACGCGGGGCGTCGGGCTCCGGGCACCACGAATGCCGGACGTGAAGGGGAGGACGGAGGCGCGTAGACGCGGCTGG
Downstream sequence
ATTCTTCTTTCTGACCCTTAGCTTTCTGTAAAACAGTGAGCAGCCCATAACTGACTTAAATTCTGAAATGGGTTAAGAGCAAATTTCTGAAGCTTGCCTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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