CABIN1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002736
Fusion event
HBV-CABIN1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr22
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
24533599/24137632 (Hg38)
End
24533599/24137632 (Hg38)
Location type
Intronic
Target gene
CABIN1
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-151a-3p ; hsa-mir-320a ; hsa-mir-25-3p ; hsa-mir-16-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-1286/Upstream/1251253; hsa-let-7a-3/Downstream/1318014;
Nearest TSS
ENST00000624155/Upstream/39519; ENST00000495121/Downstream/18206;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/126022, chr22-CpG: 70/Downstream/18382
Nearest cancer related gene
CABIN1(OG, No orient, 0)
Upstream sequence
CCCAGACTGGGTGTTTTGGTGGTTTTGCCACTTCCAGGACAGTTGTTTGTTCCTCCATGCTTCCCAGTGACCTGCTGCTTTTACCATCGTTTGGGGCCTC
Downstream sequence
TGTCCTCCTCTGCTTTCTTACCTCTTCTCTTTAGAGATAGGTTTGGGCTACTTGTGCTCCTTGAGCTATGCCTAGTGTCCAGTATGTCAAGAAATGCTGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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