MSRB3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002762
Fusion event
HBV-MSRB3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
65690497/65296717 (Hg38)
End
65690497/65296717 (Hg38)
Location type
Intronic
Target gene
MSRB3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-192-5p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-197-3p ; hsa-mir-4662a-5p ; hsa-mir-193b-5p ; hsa-mir-1193 ; hsa-mir-4716-5p ; hsa-mir-2392 ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p
Nearest miRNA
hsa-let-7i/Upstream/674112; hsa-mir-1178/Downstream/726903;
Nearest TSS
ENST00000382841/Upstream/17232; ENST00000645872/Downstream/8388;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/17247, chr12-CpG: 56/Downstream/432291
Upstream sequence
ctgcactgcctAGACAGCAATACAGGATACCCTAGTCCCTGGGAACTAGGACACTACGCACAAAGATGAAGGAAAACAGGAAGTGCCATTTGTTCAGTGA
Downstream sequence
TACTAAAACATTTATTGAGCCTTTATTTTACAGAAGTGAAAGACCACTGACTACTCTCAAGGAGTTTAAAAGAGAAACAGATTTATGAACCTAAACTTCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate