Basic Information
VIS ID
TVIS10002783
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
43392921/43425183 (Hg38)
End
43392921/43425183 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA6H
Target gene
ABCC10 ; MIR6780B
miRNAs that regulate target gene
hsa-mir-183-5p
Nearest miRNA
hsa-mir-10398/Upstream/1691573; hsa-mir-10524/Downstream/9359;
Nearest TSS
ENST00000381078/Upstream/55705; ENST00000502549/Downstream/2183;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/55089, chr6-CpG: 51/Downstream/2267
Upstream sequence
TCCAAGTAGATTTCAAGCAAGGTGTCTCACCCTAACCTGGGAAGTTAAGGATGTTAAATTATTTGATAAATTAAGTCATTAGTACATCCTGGAAAAACTT
Downstream sequence
ctgcccggccgccccgtctgagaagtgaggagcccctccgcccagcagccgccccgtctgagaagtgaggagcccctccgcccggcagctgccctgtctg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate